货号:13188-1 KU | 规格:1 KU | 目录价:¥6384 |
货号:13188 | 规格:250 U | 目录价:¥2142 |
产品详情
产品名称:
Thrombin (human)
别名:
Activated Factor II [IIa]
产品描述:
Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin and potentiates the procoagulation process by activating factors V, VIII, XI, and XIII.{12316} Conversely, thrombin aids the anticoagulant process by activating protein C.{8110} Activated protein C inhibits activated factors V and VIII ultimately down-regulating further thrombin production. Thrombin is often used as a potent platelet activator in vitro. Platelet responses to thrombin are mediated through protease-activated receptors (PARs). {15268} Thrombin-mediated signaling regulates a diverse range of metabolic processes including activation of phospholipases in platelets, endothelial cells, and cardiac myocytes.{6006}
保存温度:
-80
运输温度:
-80
产品形式:
5 mM sodium citrate, pH 6.5, containing 0.01% PEG and 20 mM sodium chloride
有效期:
365
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