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    NEDD8-AMC (human) (rec.) (untagged)
    品牌:Adipogen
    货号:SBB-PS0044-C050 规格:50 ug 目录价:¥4088
    产品详情
    产品名称:
    NEDD8-AMC (human) (rec.) (untagged)
    别名:
    Neural Precursor Cell Expressed Developmentally Down-Regulated 8; Neddylin
    产品描述:
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8) is a ubiquitin like protein that plays an important role in regulating development and the cell cycle. NEDD8 is conjugated to a target protein via a signaling cascade similar to ubiquitin: a NEDD8 specific E1 activating enzyme (APPBP1/UBA3) adenylates the c-terimnus of NEDD8 which is than subsequently passed to an E2 conjugating enzyme (UBE2M or UBE2F) that facilitates covalent attachment of NEDD8 to a cullin subunit of an SCF E3 ubiquitin ligase. NEDD8-Rh 110 can be used as a substrate for enzymes exhibiting deNEDDylating activity, e.g UCH-L3, UCH-L1, COP9 Signalosome and NEDP1. This product consists of a full-length, mature NEDD8 polypeptide (amino acids 1-76) recombinantly expressed in E.coli, conjugated on its C-terminus to a quenched AMC110 dye.
    宿主来源:
    E. coli
    偶联:
    AMC
    产品浓度:
    Lot dependent.
    保存温度:
    -80°C
    运输温度:
    Dry Ice
    预期分子量:
    ~8.7kDa
    产品形式:
    liquid
    存储溶液:
    Liquid. In 50mM MES pH 6.0, 150mM sodium chloride.
    有效期:
    Stable for at least 1 year after receipt when stored at -80°C.
    产地:
    瑞士
    纯度:
    >97% (LCMS)
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