货号:SBB-PS0043-C050 | 规格:50 ug | 目录价:¥3304 |
产品详情
产品名称:
Ubiquitin-AMC (human) (rec.) (untagged)
别名:
Ub-AMC; Ub-7-Amido-4-methylcoumarin
产品描述:
Ubiquitin is a 76 amino acid post-translational modifier expressed throughout all tissues in eukaryotic organisms. The many roles of ubiquitin modification include proteasomal degradation, signal transduction, inflammatory response, and DNA damage repair. Ubiquitin modification occurs through a pyramidal cascade of an E1 activating enzyme, E2 conjugating enzymes, and an E3 ubiquitin ligases. This enzymatic cascade results in modification of a epsilon-amine of a lysine residue on a substrate protein. Substrates may either be mono or poly-ubiquitinated by M1, K6, 11, 27, 29, 33, 48 or 63 linkages. Removal of ubiquitin from a substrate protein occurs via deconjugating enzymes, of which there are nearly 100 known enzymes with various specificities.
宿主来源:
E. coli
偶联:
AMC
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~8.7kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM MES pH 6.0.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>99% (LCMS)
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