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折扣/货期| 货号：SBB-PS0003-C050 | 规格：50 ug | 目录价：￥4914 |
产品详情
产品名称:
NEDD8 (human) (rec.) (Rhodamine 110)
别名:
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8; Neddylin; Rub1
产品描述:
NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8) is a ubiquitin like protein that plays an important role in regulating development and the cell cycle. NEDD8 is conjugated to a target protein via a signaling cascade similar to ubiquitin: a NEDD8 specific E1 activating enzyme (APPBP1/UBA3) adenylates the C-terminus of NEDD8 which is than subsequently passed to an E2 conjugating enzyme (UBE2M or UBE2F) that facilitates covalent attachment of NEDD8 to a cullin subunit of an SCF E3 ubiquitin ligase. NEDD8-Rhodamine 110 can be used as a substrate for enzymes exhibiting deNEDDylating activity, e.g UCH-L3, UCH-L1, COP9 Signalosome and NEDP1.
宿主来源:
E. coli
偶联:
Rhodamine
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~9kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM MES pH 6.0, 150mM sodium chloride.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>97% (LCMS)
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