X连锁α-地中海贫血／精神发育迟滞（又叫ATR-X综合征）是一种X连锁遗传的精神发育迟滞综合征。大约有一半的患者已发现有ATRX基因突变。转录调节因子ATRX也称为ATP依赖性解旋酶ATRX。X连锁核蛋白（XNP）或X连锁解旋酶II是由ATRX编码的蛋白质。ATRX基因的突变与X连锁精神发育迟滞（XLMR）综合征相关，常伴有α-地中海贫血（ATRX）综合征。

产品详情：

类型：多克隆抗体

来源：Rabbit IgG

应用： IHC,WB,ICC-IF

反应种属：human

免疫原：Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRR

缓冲液组成：40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative

应用实例：

Immunohistochemical staining of human uterine cervix shows moderate to strong nuclear positivity in sequamous epithelial cells.

WB analysis in A549 cells transfected with control siRNA, target specific siRNA probe#1 and #2, using anti-ATRX antibody. Remaining relative intensity is presented. Loading control:anti-GAPDH.

mmunofluorescent staining of human cell line A549 shows localization to nucleoplasm and nuclear bodies. Antibody staining is shown in green.

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