货号:GTX63902 | 规格:100μl | 目录价:¥5300 |
产品详情
产品名称:
Src (phospho Tyr416) antibody [EPR6239(2)]
别名:
SRC proto-oncogene, non-receptor tyrosine kinase , ASV , SRC1 , THC6 , c-SRC , p60-Src
反应种属:
Human, Rat
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
Based on sequence homology, this antibody may cross with other Src family members such as YES1 , FYN proteins when phosphorylated at the equivalent sites.
同种型:
IgG
免疫原:
A phospho specific peptide corresponding to residues surrounding Tyrosine 418 of human Src was used as an immunogen. The Tyr418 of human Src is equivalent to Tyr416 of chicken Src.
克隆性:
Monoclonal
克隆号:
EPR6239(2)
纯化方式:
Tissue culture supernatant
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
60
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 50% Glycerol, 0.01% Sodium azide.
产地:
美国
功能与背景:
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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