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Rp-Adenosine-5'-O-(1-thiotriphosphate) (sodium salt)
品牌:Cayman
货号:38535 规格:2.6 mg 目录价:¥3360
产品详情
产品名称:
Rp-Adenosine-5'-O-(1-thiotriphosphate) (sodium salt)
别名:
Rp-ATP-α-S
产品描述:
Rp-Adenosine-5'-O-(1-thiotriphosphate) (Rp-ATP-α-S) is an isomer of the sulfur-containing nucleotide derivative ATP-α-S and an agonist of the purinergic P2Y1 receptor.{67377} It increases calcium mobilization in HEK293 cells expressing the human P2Y1 receptor (EC50 = 75 nM). Rp-ATP-α-S binds to washed isolated human platelets (Ki = 156 nM), inhibits ADP-induced aggregation of isolated human platelet-rich plasma (PRP; pA2 = 4.74), and inhibits cAMP production induced by prostaglandin E1 (PGE1; Item No. 13010) in isolated human PRP (pA2 = 5.26).{67378,49795} It also induces relaxation of carbamoylcholine-preconstricted guinea pig taenia coli strips (EC50 = 56 nM).{69380} Rp-ATP-α-S has been used in the synthesis of cyclic dinucleotides that are recognized by bacterial riboswitches.{49796}
保存温度:
-80
运输温度:
-80
预期分子量:
611.2
产品形式:
A solution in water
有效期:
730
纯度:
≥95%
分子式:
C10H12N5O12P3S • 4Na
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