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折扣/货期| 货号：450-58-100ug | 规格：100ug | 目录价：￥12819 |
| 货号：450-58-1mg | 规格：1mg | 目录价：￥51397 |
| 货号：450-58-20ug | 规格：20ug | 目录价：￥2850 |
| 货号：450-58-250ug | 规格：250ug | 目录价：￥22431 |
| 货号：450-58-500ug | 规格：500ug | 目录价：￥33338 |
| 货号：450-58-5ug | 规格：5ug | 目录价：￥1169 |
产品详情
产品名称:
Recombinant Murine Artemin
别名:
ART, ARTN, Enovin, Neublastin
产品描述:
Artemin is a disulfide‐linked homodimeric neurotrophic factor structurally related to GDNF, neurturin and persephin. These proteins belong to the cysteine knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, persephin and neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRα (alpha1‐alpha4) receptors. Artemin prefers the receptor GFRalpha3‐RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia, such as sympathetic, neural crest and placodally‐derived sensory neurons, and dopaminergic midbrain neurons. The functional human artemin ligand is a disulfide‐linked homodimer of two 12.0 kDa polypeptide monomers. Each monomer contains seven conserved cysteine residues, one of which is used for interchain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine‐knot configuration. Recombinant Murine Artemin is a disulfide‐linked homodimer formed by two identical 113 amino acid subunits with a calculated molecular weight of 24.2 kDa.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
12.1 kDa
产品形式:
Standard
产地:
美国
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