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Fluticasone propionate
品牌:Adipogen
货号:CDX-F0325-M005 规格:5 mg 目录价:¥询价
货号:CDX-F0325-M025 规格:25 mg 目录价:¥询价
产品详情
产品名称:
Fluticasone propionate
别名:
Fluticasone 17-Propionate; (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester; CCI 18781
产品描述:
Fluticasone propionate is a synthetic corticosteroid. It is a high affinity, selective glucocorticoid receptor agonist (Kd = 0.5nM). It is used as an anti-inflammatory agent for asthma. It has low systemic bioavailability and has been investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to asthma, allergic rhinitis and other airway diseases. It potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis in vitro. It also potentiates KV1 channels (EC50 = 37nM).
宿主来源:
Synthetic
保存温度:
+20°C
运输温度:
Ambient
预期分子量:
500.57
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at RT.
产地:
瑞士
纯度:
>97% (NMR)
CAS号:
80474-14-2
分子式:
C25H31F3O5S
溶解度:
Soluble in DMSO (20mg/ml) or DMF (20mg/ml).
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