产品规格

1/5/25/50/100mg

抗体亚型

Mouse IgG1, κ

推荐同型对照

InVivoMAb mouse IgG1 isotype control, unknown   specificity（货号：BE0083）

推荐抗体稀释液

InVivoPure™ pH7.0   Dilution Buffer（货号：IP0065）

免疫原

Human CD3ε

应用

in vivo T cell depletion in humanized mice

ex vivo T cell inhibition for xenographs

Flow cytometry

产品形式

PBS , pH 7.0

Contains no stabilizers or preservatives

内毒素水平

<2EU/mg (<0.002EU/μg)

使用 LAL gel   clotting 测定

纯度

>95% Determined by SDS-PAGE

无菌处理

0.2 μM filtered

生产形式

从组织培养上清液中纯化得到。

纯化形式

Protein G

RRID

AB_2687713

分子量大小

150 kDa

保存条件

抗体原溶液应保存在4°C条件下，不要冷冻保存。

in vivo T cell depletionn

Woo, J. H., et al. (2010). “Pharmacology of   anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials.” Methods Mol Biol 651: 157-175.

Flow cytometry

Rossi, N. E., et al. (2008). “Differential   antibody binding to the surface alphabetaTCR.CD3 complex of CD4+ and CD8+ T   lymphocytes is conserved in mammals and associated with differential   glycosylation.” Int Immunol 20(10): 1247-1258.