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折扣/货期| 货号：AG-20B-0014-C100 | 规格：100 ug | 目录价：￥3720 |
产品详情
产品名称:
anti-NLRP3/NALP3, mAb (Cryo-2)
别名:
NACHT-, LRR- and PYD-containing Protein 3; NLRP3; Cryopyrin; Cold Autoinflammatory Syndrome 1 Protein
产品描述:
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
ICC, IHC, IP, WB, CHIP
靶标/特异性:
Recognizes mouse and human NLRP3/NALP3.
同种型:
Mouse IgG2b
免疫原:
Recombinant mouse NLRP3/NALP3 (pyrin domain/aa 1-93).
克隆号:
Cryo-2
产品浓度:
1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
纯度:
>95% (SDS-PAGE)
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