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货号:GTX84890 规格:100μl 目录价:¥7300
产品详情
产品名称:
ALDH2 antibody [4H2]
别名:
aldehyde dehydrogenase 2 family member , ALDH-E2 , ALDHI , ALDM
反应种属:
Human
宿主来源:
Mouse
实验应用:
FACS, ICC/IF
同种型:
IgG3
免疫原:
Full length human recombinant protein of human ALDH2 (NP_000681) produced in HEK293T cell.
克隆性:
Monoclonal
克隆号:
4H2
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
56
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
产地:
美国
功能与背景:
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]
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